Formulation of two lipid-based membrane–core nanoparticles for FOLFOX combination therapy

Jianfeng Guo, Leaf Huang

Published: 2022-05-31 DOI: 10.1038/s41596-022-00698-3

Nanoformulations

FOLFOX therapy

Lipid-based nanoparticles

Antitumor efficacy

Targeted drug delivery

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FOLFOX is a combination of folinic acid (FnA), 5-nobreakfluorouracil (5-Fu) and oxaliplatin (OxP). It has been used as the standard treatment for colorectal cancer (CRC) and hepatocellular carcinoma (HCC). This treatment is effective, but its high toxicit
Introduction
Materials
Procedure 1: Nano-Folox
Procedure 2: Nano-FdUMP
- Preparation of Ca3(PO4)2•FdUMP nanoprecipitates
- Formulation of Nano-FdUMP
Procedure 3: physicochemical characterization
Timing
Anticipated results
- References
References
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Formulation of two lipid-based membrane–core nanoparticles for FOLFOX combination therapy

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