Isolation of mouse pancreatic islet Procr+progenitors and long-term expansion of islet organoids in vitro

Jingqiang Wang, Daisong Wang, Xinyi Chen, Shubo Yuan, Lanyue Bai, Chunye Liu, Yi Arial Zeng

Published: 2022-04-07 DOI: 10.1038/s41596-022-00683-w

Procr+ progenitors

islet organoids

in vitro expansion

beta cell generation

glucose homeostasis

AI 解读

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Insulin production is required for glucose homeostasis. Pancreatic islet β cells are the only cells that produce insulin in humans; however, generation of functional β cells invitro from embryonic or adult tissues has been challenging. He
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ACKNOWLEDGMENTS

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Isolation of mouse pancreatic islet Procr+progenitors and long-term expansion of islet organoids in vitro

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